SUMMARY OF DATA FOR CHEMICAL SELECTION Oligomeric Proanthocyanidins from Grape Seeds and Pine Bark BASIS OF NOMINATION TO THE CSWG

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Based on the structures of identified active ingredients, the phenolic compounds extracted from grape seeds and pine bark would not be expected to be genotoxic. Indeed, the inventor of pycnogenol states that this product was tested in Salmonella typhimurium and was negative. Substantial health claims for grape seed and pine bark extracts, including some studies showing tumor inhibition, make them attractive materials for further study. Antioxidants, especially polyphenols, in red wine have been proposed as an important contributory factor to the protective effect of regular alcohol use against atherosclerotic cardiovascular disease. Grape seed and pine bark extracts may have the beneficial effects of red wine without its detrimental effects.

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SUMMARY OF DATA FOR CHEMICAL SELECTION Oligomeric Proanthocyanidins from Grape Seeds and Pine Bark BASIS OF NOMINATION TO THE CSWG

Based on the structures of identified active ingredients, the phenolic compounds extracted from grape seeds and pine bark would not be expected to be genotoxic. Indeed, the inventor of pycnogenol states that this product was tested in Salmonella typhimurium and was negative. Substantial health claims for grape seed and pine bark extracts, including some studies showing tumor inhibition, make th...

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تاریخ انتشار 2001